7 Comments

This is the best article I've read on the subject. I finally understand all the jargon I had been plowing through, and can see real benefits from knowing epigenetics.

Thank you, Nita.

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Thanks, Tom! Glad it’s more actionable and less theoretical now. Hope you’re doing well!

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Do you plan to put out a book with a compilation of your postings.? I'd be the first in line to get a copy.

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Thanks, that means a lot! At the very least, I'd love to host live cohorts to communicate some of these concepts more effectively.

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Really wonderful to read this information, and so well thought out. Brilliant.

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Thank you, hope it helps!

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Hello, and you forced me to come comment because rumination and stoicism. Well, and you liked a comment.

I am curious about this list:

*Diet and Nutrition: Nutrients like vitamin B12, folic acid, choline, and betaine act as methyl donors, affecting DNA methylation patterns.

*Exercise and Lifestyle Choices: Physical activity and healthy habits can positively influence gene expression.

*Sunlight Exposure and Circadian Rhythms: Natural light and sleep patterns impact epigenetic regulation.

*Stress and Trauma: Psychological factors can induce epigenetic changes affecting mental and physical health.

*Exposure to Pollutants: Environmental toxins, such as endocrine disruptors, can alter epigenetic marks.

Do you see a hierarchy to these? The first three seem to me on a first pass as very modern problems. And what I mean is that maybe beginning in 19th century, but for sure accelerating in the 20th we have diet shifts toward processed foods, inside and sedentary jobs, and a disruption of natural light and sleep patterns. The other two seem like they may be more or less consistent through history, just different causes. War and disease, raw sewage and the like.

The first three also seem like maybe they are under more direct control of the individual and so maybe focusing on those three would have a disproportionate salutary effect. Thoughts?

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